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Tablet Dissolution Tester DS 14000 Smart with Piston Pump

Tablet Dissolution Tester DS 14000 SMART with Piston Pump

The dissolution tester DS 14000 Smart with piston pump is the core of our dissolution testing system. Intelligent sampling system is used where the sampling tubes are accurately moved to USP sampling position. For sample collection option of standard vials and HPLC vials is available. The needles can pierce through the septa and collect the samples so that there is no spillage.

1 million cycles for the piston pump are guaranteed with easy serviceability and maintenance. The dissolution tester comes with  21 CFR Part 11 software as a standard with LAN connectivity for data backup on network shared folders. QWERTY Keyword for entries of Sample Name, Sample Number and Identification Number for authentication. More than 1000 methods can be stored due to large memory size in the dissolution apparatus.

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Standard Features of DS 14000 SMART with Piston Pump
  • Advance Micro – controller (Arm Core )User-friendly, complies with current USP , IP ,BP & EP and ASTM specifications.
  • Mono shaft design with easy changeover between Apparatus I & II eliminates routine height validation as per USP.
  • Automatic stirrer 25 mm depth positioning (as per USP )
  • Vessels, paddles and Basket are Laser marked with serial numbers for traceability
  • Automated Tablet dispenser drops 12 dosage form at single instance
  • The conical shape low evaporation recover y lids reduces media loss during long run.
  • Easy placement and locking of vessels, the Easealign system allows the vessels to simply slide into the place (Bionet Locking).
  • Facility to monitor Vessel temp ,with an external Digital Temperature Sensor
  • 7’’ Colour High resolution Display with touch screen interface
  • External vibration free flow water circulator
21 CFR Part 11 Compliance
  • Audit Trail for all activities with search facility, report generation and printing.
  • 200 and more User ID’s with alphanumeric entries of user name, password and role based privileges selection.
  • Multi-level roles with password protection,expiry & complexity
  • User authentication is per formed for each and every operation done by user.
  • PDF report file can be created through print.
  • Electronic signature functionality.
  • Data Backup and Restore facility available.
  • LAN (Ethernet) connectivity for Data backup on Network shared folder
Regulatory Compliance
  • DS 14000 SMART with Piston Pump meets all requirements relating to validation, qualification and calibration.
  • Appropriate qualification documents (I.Q. / O.Q.) can be supplied with the instrument.
Additional Features
  • Built in validation Software
  • Facility to RINSE the entire sampling path in between sampling time - point to eliminate contamination & carryover
  • Specially developed cleaning system to clean the entire sampling path after each run
  • Facilities to perform the dissolution test using two buffers (Buffer changing) to cater the application of enteric coating tablets.
  • Recovery Test facility to study 100% Drug Dissolution.
  • Split & on-time interval
Intelligent Sampling System
  • Automated sampling as per USP Specifications. Sampling tubes are lowered in the media only at the time of sampling and withdrawn immediately after sampling, thus no part of the assembly contributes motion, agitation or vibration.
  • Sampling tubes are accurately moved to the USP sampling position i.e. a zone mid way between the sur face of media and the top of paddle/basket parameters, not less than 1 cm from the vessels wall as selected in the method.
  • 6 vessels temperature monitoring system automatically measures & records the temperature of individual vessel at specified sample points.
  • Inert PTFE Fluoropolymer Carrier Tubing
Piston Pump - PP 12
  • Piston Pump - PP 12 is ideal for sample withdrawal from12 channels.
  • The Piston Pump - PP 12 with inert ceramic rotor overcomes all absorption issues.
  • Accuracy better than ±2%(@10mL)
  • Rinse function for reducing carryover issues.
  • Surfactant Media Compatibility.
Sample Collection
  • 12 X 8 X2 sets of samples can be collected. For more sampling interval, 24 X 8 collection trays are available.
  • Option of 1.5ml & 2ml HPLC vials 24*8 tray is available.
  • Wide mouth vial to minimise SLS spillover problem due to foaming Characteristics
  • Auto recognition sensor for tray with alarm facility for collection sample
  • Easy positioning with respect to vials or test tube tray for easy changeover
Typical Specification
DISSO SMART 14000 with Piston Pump
DS14000 with Piston Pump
Dissolution Vessel

Option for Polycarbonate / Glass Vessels (clear, amber, peak vessels, 250, 150 & 100 ml dissolution vessels available). 


7" Colour High Resolution Touch Screen Display

40*2 LCD Display (Alphanumeric)


20 to 350 RPM

20 to 250 RPM

RPM Accuracy

± 1 RPM

Temprature Range

20° to 55° degree

Temp Accuracy

± 0.1° C








4 Role(Admin,Manager,Supervisor,Operator)

2 Role(Admin & User)




Test Report


Last Report

21 CFR Compliance

Yes (Optional)

Yes( EDC Software)




E Signature



Sampling Interval



Sample Interval Time

1 Min to 1200 hrs

1min to 720 hrs

Pump Used for Sample Collection

Piston Pump



Cleaning Cycle

Programmable multiple cleaning & drying cycles

Sample Collector Type

Covered (no evaporation, protects samples from
dust, dirt & contamination)


HPLC Vials Tray


Auto Tablet Dispenser



Tray detection & identification

Special sensor for detecting the alignment and
type of tray to prevent any human error


Contact parts

All Contacts Parts are inert

Sample Collection

12*8*2 Sample Collection Tray Tray.(24*8 Optional)

12*6*2 Sample Collection Tray Tray.(24*6 Optional)

Automatic Vessel Centering

Yes (Complies as per US FDA division of
pharmaceutical analysis (Ref. Document no.

Center Shaft

± 0.5mm

Lift Mechanism

Motorized (Automatic) for accurate height


Isolated temperature controller (vibration-free & precise) with wake up & sleep modes (saves time & energy) (1KW)


MonoShaft - Easy Switch Over between Paddle & Basket

Height Adjustment

Automatic height adjustment


Unique design of USP apparatus
I, II, V, VI & intrinsic dissolution can be used. Also Small Volume Dissolution kit 250ml & 150ml can be used.

Laser Marking on Accessories


Water Bath

Clear acrylic molded water Bath 

Water Level Sensor


Power Failure


LABINDIA reserve the right to change specification without notice as part of its continuous product development.

  • QWERTY Keyword for entries of Sample Name, Sample Number and Identification Number for authentication.
  • Built-in Real Time Clock (RTC) for date and time on display and on printout.
  • Factory entered CUSTOMER NAME with Instrument Serial Number on report printouts
  • Non-Volatile memory storage methods with parameters.
Tablet Dissolution Testers