PermeGear’s Automated Diffusion Cell Systems incorporate In-Line Cells, a peristaltic pump, a fraction collector, and a heater/circulator into a versatile system for analyzing flux over time. Collection vials are at the option of the user, racks for 20ml 28mm diameter scintillation vials are provided. When ordering, please advise the size vials you will be using so we can include the correct Vial Racks. Vials ARE NOT supplied by PermeGear.
All PermeGear automated diffusion cell systems are based on the continuous flow principle. A multi-channel peristaltic pump draws receptor solution from a reservoir through a distribution manifold and sends it to the In-Line Cells. The cells are warmed to 32ºC by a heater/circulator that pumps water through the Cell Warmer in which the In-Line Cells are located. After filling the receptor chambers of the cells and purging the system of bubbles, the subject compound is then placed in the donor chambers of the cells. From that time, the fluid is collected in the vials of the fraction collector at user set time intervals. The vials are taken for analysis manually after the sampling time has elapsed.
Overall pricing for the ILC07 System is dependent on the configuration of the In-Line Cells used.