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Dissolution Apparatus with Peristaltic Pump

Dissolution Apparatus DS 8000 with Peristaltic Pump

The Labindia Tablet dissolution Apparatus DS 8000 with peristaltic pump is an ideal semi automated dissolution testing system with auto sampler that collects the sample for later analysis. Peristaltic pump and auto sampler are controlled by the dissolution apparatus.

The 12 channel peristaltic pump is from Ismatec which is Swiss made for high accuracy and long durability. Samples for dissolution testing can be collected in test tubes or standard vials or HPLC vials.

Tablet dispenser with low evaporation lids ensure no media loss during long run. All reports and data can be printed with a printer using parallel or serial port.

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Standard Features of Dissolution Apparatus DS 8000 with Peristaltic Pump
  • User-friendly, complies with current USP, IP, BP & EP and ASTM specifications.
  • Alphanumeric polyester soft keys for keyboard.
  • External vibration free Water Circulator for uniform water circulation with audible and low water level alarm.
  • Mono shaft design with automatic adjustment for 25 mm depth setting with easy changeover between Apparatus I & II eliminates routine height validation as per USP.
  • Paddles, Baskets and Vessels are laser marked with serial numbers for traceability.
  • Tablet dispenser drops 6 dosage form at single instance.
  • The conical shape low evaporation recover y lids reduces media loss during long run.
  • Facility to monitor Vessel temp, with DTS Technology (Digital Temperature Sensor)
Additional Features
  • Facility to RINSE the entire sampling path in between sampling time point to eliminate contamination & carryover
  • Specially developed cleaning system to clean the entire sampling path after each run.
  • Facilities to perform the dissolution test using two buffers (Buffer changing) to cater the application of enteric coating tablets.
  • Recovery Test facility to study 100% Drug Dissolution.
  • Split & on-time interval
Intelligent Sampling System
  • Automated sampling as per USP Specifications. Sampling tubes are lowered in the media only at the time of sampling and withdrawn immediately after sampling, thus no part of the assembly contributes motion, agitation or vibration.
  • Sampling tubes are accurately moved to the USP sampling position i.e. a zone midway between the surface of media and the top of paddle/basket parameters, not less than 1 cm from the vessels wall as selected in the method.
  • 6 vessels temperature monitoring system automatically measures and records the temperature of individual vessel at specified sample points.
Peristaltic Pump
  • Imported Pump with click-n-go Cassette design provides defined and repeatable occlusion conditions.
  • Fixed length pump tubing with stopper for sampling volume accuracy.
  • Volume calibration through software.
  • Tygon pump tubing for SLS Compatibility with long life.
  • High repeatability on all Channels.
  • 12 actively driven stainless steel rollers.
Sample Collection
  • 10 X 6 or 16 X 6 sets of samples can be collected. For more sampling interval, 24 X 6 collection trays are available.
  • Option of 1.5ml & 2ml HPLC vials tray is available.
  • Over Head Design for electronic safety and fail safe operation.
  • Sensor to locate proper position of tray with alar m facility for collection of sample.
  • Wide mouth vial to minimise SLS spillover problem due to foaming characteristics
  • Easy positioning with respect to vials or test tube tray for easy changeover
Regulatory Compliance
  • DS 8000 with Peristaltic Pump meets all requirements relating to validation, qualification and calibration.
  • Appropriate qualification documents (I.Q. / O.Q.) can be supplied with the instrument.
Typical Specification
DS 8000 with Peristaltic Pump

Micro controller based (Advanced version of microprocessor


40 x 2 line back lighted liquid crystal display (LCD)


Alphanumeric splash waterproof polyester soft keys.

Method Storage

15 programs with parameters

Data Storage

Available with Non-Volatile memory.

Water Bath

17 litres capacity with built-in water level sensor / Front located drain tap for easy draining of the water bath.

Bath Circulation

External vibration free water circulator

Temperature Range

20°C to 55°C

Temperature Resolution


Temperature Control Accuracy

up to 45°C ±0.1°C & >45°C up to 55°C ±0.2°C

Temperature Sensor

DTS - Digital Temperature Sensor

Evaporation Loss

1% (at 50 RPM / 37?C / 1000mL / 24hrs)

Paddle/Basket Shaft Speed Range

20 to 350 RPM

RPM Speed Accuracy

20 to 300 RPM ±0.5 RPM & Above 300 RPM ± 0.8 RPM

Dissolution Vessel

option for Polycarbonate / Glass Vessels (clear, amber, peak vessels, 250, 150 & 100 ml dissolution vessels available)

Sampling Time Selectivity

Fixed/Programmable (varying intervals)

Time Interval Selectivity

In steps of 1 minute

Maximum Number of Intervals


Dissolution Process Time

1 min. to 720 hours

6 Channel Temperature Reader

Optional - with Temperature Reader

Report Format

a) GLP & Pharmacopeia compliant
b) Program parameter report


110 / 220 V AC - 50 Hz / 60 Hz

Environmental Operating Conditions

a) Operation: Indoor.
b) Temperature: Ambient to 45ºC.
c) Humidity: 5 to 90% non-condensing.


71.5 x 60 x 70.5 cms. (W x D x H)


80 kgs. approx.


printer with parallel port


LABINDIA reserve the right to change specification without notice as part of its continuous product development.

  • Alphanumeric entries of Sample Name, Sample Number and Identification Number for authentication.
  • Built-in Real Time Clock (RTC) for date and time on display and on printout.
  • Daily Auto Incremented Run Number and factory entered CUSTOMER NAME with Instrument Serial Number on report printouts
  • Non-Volatile memory storage of 15 methods with parameters.
  • Two tier password protection of Admin and User
  • Reports can be obtained even after Resetting / Power off / Power failure conditions.
  • Error indication helps user to trace the problem.
  • Audible indication for ready state of instrument.
Tablet Dissolution Testers