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Tablet Dissolution Tester DS 14000 with Piston Pump Manufacturers India

Tablet Dissolution Tester DS 14000+ with Piston Pump

The tablet dissolution tester DS 14000 with piston pump is a perfect solution for dissolution testing for high throughput.  Automated sampling as per pharmacopeia allows sampling tubes to be lowered in the media only at the time of sampling and withdrawn immediately thus no part of the assembly contributes motion, agitation or vibration.

This dissolution tester comes with a high-pressure piston pump that can have high flow rates up to 25ml/min with accuracy upto 1%. Different sample collection options available and all the trays have sensor to locate proper position of tray with alarm.

  There is also a recovery test facility in dissolution tester 14000 to check 100% drug dissolution. With many more features, the tablet dissolution system from labindia is one of the best in terms of price, quality, and performance.

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Standard Features of Dissolution Tester DS 14000+ with Piston Pump
  • Advanced, Micro-Controller based: User-friendly, complies with current USP, BP, IP, JP & EP specifications. It fulfills all requirements relating to ASTM & FDA Mechanical Calibration.
  • Splash waterproof keyboard: Alphanumeric polyester soft keys for keyboard.
  •  Moulded water bath with 12+2 (6+1 & 6+1) vessel configuration enables comparative studies.
  •  External vibration free Water Circulator: for uniform water circulation, with audible, low water level alarm, with indication on display for safety.
  •  Mono shaft design with automatic adjustment for 25 mm depth setting with easy changeover between Apparatus I & II eliminates routine height validation as per USP.
  • Paddles, Baskets and Vessels are laser marked with serial numbers for traceability.
  • Tablet dispenser - drops 12 dosage form at single instance.
  •  Low Evaporation Lids: The conical shape low evaporation recovery lids reduces media loss during long run. 
  • Integrated pre-centered lids; no manual removal or positioning of lids. This ensures automatic vessel centering and precise positioning of paddle/basket with shaft without any special tool as per pharmacopeia requirements.
  • State-of-the-art design: Easy placement and locking of vessels, the Easealign system allows the vessels to simply slide into the place (Bionet Locking). Once placed, vessels do not float even when empty.
  • Facility to monitor Vessel temp., with DTS Technology (Digital Temperature Sensor)
Intelligent Sampling System
  • Automated sampling as per USP Specifications. Sampling tubes are lowered in the media only at the time of sampling and withdrawn immediately after sampling, thus no part of the assembly contributes motion, agitation or vibration.
  • Sampling tubes are accurately moved to the USP sampling position i.e. a zone mid way between the sur face of media and the top of paddle/basket parameters, not less than 1 cm from the vessels wall as selected in the method.
  • 12 vessels temperature monitoring system automatically measures & records the temperature of individual vessel at specified sample points.
Pump System - PP 12
  • Piston Pump - PP 12 is ideal for sample withdrawal from 12 channels.
  • The inert ceramic rotor overcomes all absorption issue
  • Accuracy better than ±2%.(@10mL)
  • Rinse function for reducing carryover issues.
  • Surfactant Media Compatibility.
  • Option of sample dilution available (not recommended before final filtration)
Sample Collection
  • 12 X 6 X2 sets of samples can be collected. For more sampling interval, 24 X 6 collection trays are available.
  • Option of 1.5ml & 2ml HPLC vials is available.
  • Over Head Design for electronic safety and fail safe operation.
  • Sensor to locate proper position of tray with alar m facility for collection of sample
  • Wide mouth vial to minimise SLS spillover problem due to foaming characteristics
Regulatory Compliance
  • DS 14000+ with Piston Pump meets all requirements relating to validation, qualification and calibration.
  • Appropriate qualification documents (I.Q. / O.Q.) can be supplied with the instrument.
Additional Features
  • Facility to RINSE the entire sampling path in between sampling time - point to eliminate contamination & carryover
  • Specially developed cleaning system to clean the entire sampling path after each run
  • Facilities to perform the dissolution test using two buffers (Buffer changing) to cater the application of enteric coating tablets.
  • Recovery Test facility to study 100% Drug Dissolution.
  • Split & on-time interval
Typical Specification



Micro controller based (Advanced version of microprocessor).


40 x 2 line back lighted liquid crystal display (LCD)


Alphanumeric splash waterproof polyester soft keys.

Method Storage

15 programs with parameters.

Data Storage

Available with Non-Volatile memory. More than 10,000 reports

Water Bath

29 litres capacity with built-in water level sensor.

Bath Circulation

External vibration free water circulator

Temperature Range

20°C to 55°C

Temperature Resolution

0.1° C

Temperature Accuracy

up to 45°C ±0.1°C & >45°C up to 55°C ±0.2°C

Temperature Sensor

DTS - Digital Temperature Sensor

Evaporation Loss

1% (at 50 RPM / 37˚C / 1000mL / 24hrs)

Paddle/Basket Shaft Speed Range

20 to 250 RPM ±0.5 RPM

RPM Speed Accuracy

20 to 300 RPM ±0.5 RPM & Above 300 RPM ± 0.8 RPM

Dissolution Vessel

Polycarbonate / Glass Vessels (clear, amber, peak vessels, 250, 150 & 100 ml. dissolution vessels available)

Sampling Time Selectivity

Fixed / Programmable (varying intervals).

Time Interval Selectivity.

In steps of 1 minute.

Sampling Volume Range

0.5 - 25.5 ml

Sampling Volume Accuracy

For 10mL, ± 0.2mL

Replenishing mode selectivity

User selectable.

Maximum Number of Intervals


Dissolution Process Time

1 min. to 720 hours.

6 Channel Temperature Reader


Report Format

a) GLP & Pharmacopeia compliant

b) Program parameter report



a) Printer: Compatible for deskjet, inject and dot matrix printer

b) RS232C: For PC Connectivity

c) 21 CFR Part 11 compliance software available (Optional)


210-230 V AC ± 10%, 50 Hz. - 60 Hz.


Environmental Operating Conditions

a) Operation: Indoor.

b) Temperature: Ambient to 45° C.

c) Humidity: 5 to 90% non-condensing.


115 x 60 x 70.5 cms. (W x D x H)


140 kgs. approx.

  • GLP Compliance:
  • Alphanumeric entries of Sample Name, Sample Number and Identification Number for authentication.
  • Built-in Real Time Clock (RTC) for date and time on display and on printout.
  • Daily Auto Incremented Run Number and factory entered CUSTOMER NAME with Instrument Serial Number on report printouts make the system foolproof.
  • Non-Volatile memory storage of 15 methods with parameters. Validation Software to validate RPM, Temperature, sampling volume & replenish volume.
  • Protects Editing, Avoids invalid entries: Two tier password  protection Admin and User
  • Ease in operation: Dissolution RUN can be started with last run parameters.
  • Facility to view Set Parameters during RUN.
  • Auto Start facility to continue the dissolution analysis in case of short power interruption (especially useful for long duration analysis of sustained release tablets).
  • Reports can be obtained even after Resetting/ Power off/Power failure conditions.
  • Error indication helps user to trace the problem.
  • Alarms and Indications: Audible indication for ready state of instrument.
  • Wake-up Alarm: This unique feature automatically turns the bath heater ON at a predetermined time.
Tablet Dissolution Testers